The independent nonprofit Center for Open Data Enterprise (CODE) and the Office of the Chief Technology Officer (CTO) at the U.S. Department of Health and Human Services (HHS) are co-hosting a series of three Roundtables to find ways to improve how health data is shared and utilized for the public good. As part of this series, CODE and the HHS Office of the CTO convened a Roundtable on Sharing and Utilizing Health Data for AI Applications on April 16, 2019. This Roundtable brought together over 70 expert stakeholders from government, industry, clinical research institutions, nonprofit organizations, and academia to discuss opportunities to share and utilize health data for artificial intelligence (AI) in healthcare. The purpose of this Roundtable was to identify high-priority health applications of AI and key issues for an HHS AI strategy to address. Participants discussed high-value health data types, challenges associated with utilizing health data for AI, and strategic considerations that HHS and other stakeholders should consider as they explore AI development in healthcare.